If you be hunting blacktail or mule deer go with the 270. Even that is a little big, but it has the range. 30-06 although popular is really too much gun. The 308 with light bullets is a good .30 choice. Ammo is a little cheaper than the others.
I like the Remington Model 7 in 308. Very light. You can carry it all day long.
I use a .223 for Texas Whitetails. They look like big German shepards. Like the Californai blacktail. I have never used anything bigger than the 6mm, (.243) And I have killed Axis, whitetail, sheep, hogs, antelope, elk, and red deer - (european elk)
Wild Phil Hick Up - owner / trainer of 2 Labrador Retrievers. Colt Lightning, STUD, Age 9, and Molly Koh Lange, Age 2 / My Deceased Friends - Jody - Age 9 (cancer), Cody - Age 16 (8/22/06 - old age) and Jazz - Age 9 (8/1/06 - cancer)