I live on Elliott Island, grew up on the Nanticoke and hunt Fishing Bay in every capacity on all sides, conditions and in general the entire area. As everyone mentioned it is a hard place to hunt so you need to have all your ducks in a row so to speak. I have canoed much of the area. I would suggest doing it this summer and seeing how you do.
The problem is not the water but the depth of the water and the bottom. The area is very deep mud. Believe me I have been over my armpits in mud, alone, cold, exhausted and unsure if I would make it to my boat alive. When the tide goes out it goes out fast more than once I have been stuck to point where I had grab my gun and do the Bataan death march to the road and I am not getting younger if you know what I mean. 2 pieces of equipment I always have is a flare gun and a road flare. Cell reception is spotty to non-existent and then who would come and get you if you do call? I carry the road flare so I can lite the marsh on fire if I ever really got it trouble and I freezing to death at least I could follow the fire line and stay warm to the road and hopefully it would attract some attention.
In the past a canoe was OK but remember if your in a canoe and you have 2 inches of water with a very soft mud bottom you are not paddling you are trying to push but you cant push because its mud and mud that sticks to your paddle making each paddle weight seemingly 40lbs. Suck, dam right that situation sucks.
Big water is also adventure. Even in the summer there are days I see no other boat and it does get rough. There are creeks I hunt and fish where I have never seen another boat in 15 years of fishing or hunting it.
So it is a question of is it worth it or not. Will you shoot ducks? Is it worth 1 black duck, one canvasback, one whatever?
Because one thing for sure is if you don't live near it or on it is a long way from home and people.
I have seen many people over the years from all over that spend all night driving from wherever and roll down the road just to put their 20K duck hunting boat in the water and report later in the day that they saw no ducks. I never see them again! Its a big place, takes a days long commitment, and its hard to hunt and scouting is required. To be honest, if you don't spend the time scouting and understanding the place then its a waste of time.
Now with all of this said I don't want to discourage you there plenty of birds there, Arkansas it isn't. Just advising you to do some exploring this summer watch the birds etc. Enjoy it for its beauty. Wave to the locals get the fire companies phone number so if you ever do get in trouble they will be the only ones that can get you quick.