Hi, welcome and can't wait to hear about your first hunt.
Here's a few tips for staying warm. First stay away from cotton, stick to fleece and wool. Cotton absorbs moisture when you start to sweat and then when you stop moving it just gets plain cold. A good base layer (long undies is a must), wool socks, a warm hat, and for me I find that having something like a neck gaiter really helps to keep the chill off. With waders, fleece pants are real nice, I actually have a pair of yoga-style fleece lounge pants that work just as well as the expensive fleece pants that Cabela's sells.
Also, those chemical hand and foot warmers are wonderful. I prefer the insole kinds for my feet, but if it's really cold I may use those, plus the toe warmers. Make sure your wader boots aren't too tight, if your boots are too tight, your feet will get cold because the blood can't circulate as well.
Another good idea is to put on your outer layers after you get to your hunting spot. That way you don't start to get to hot riding in the truck and then get cold when you get there. Same if you have a long walk to your spot. I usually have my warm hat, neck gaiter, etc, in my blind bag, and then once I sit for a little while and start to cool off I add layers. I hope that helps!
What type of area are you hunting? Out of a boat, in a blind, etc?